Friday, September 24, 2010

Asthma Drug

salbutamol
[Salbutamol is a direct-acting sympathomimetic with β-adrenergic activity and selective action on β2 receptors, producing bronchodilating effects. It also decreases uterine contractility.
Onset: Inhalation: 5-15 min; oral: 30 min.
Duration: Inhalation: 3-6 hr; oral: 8 hr; modified-release preparation: 12 hr.
Absorption: Readily absorbed from the GI tract.
Metabolism: Hepatic and in the gut wall.
Excretion: Via the urine as metabolites and unchanged drug. Some excretion in the faeces.

Asmacare tab® [ Kimia Farma ] , Azmacon tab® [ Armoxindo Farma ], Bronchosal caplet® [ Ifars ], Brondisal 2 tab® [ Global Multi Pharmalab (GMP) ], Brondisal 4 tab® [ Global Multi Pharmalab (GMP) ], Combivent unit dose vial® [ Boehringer Ingelheim ] , Fartolin Expectorant syr® [ Fahrenheit ], Fartolin tab® [ Fahrenheit ], Hivent nebules® [ Euro-Med ], Lasal cap® [ Lapi ], Pritasma tab® [ Molex Ayus ], Salbron Expectorant syr® [ Kalbe Farma ],

terbutaline
[Belongs to the class of adrenergics for systemic use, selective beta-2-adrenoreceptor agonists. Used in the treatment of obstructive airway diseases.]
Bricasma amp® [ AstraZeneca ],  Forasma tab, Lasmalin tab, Nairet amp, Neosma, Pulmobron, Sedakter, Yarisma tab.


montelukast
[Montelukast is a selective leukotriene receptor antagonist that blocks the effects of cysteinyl leukotrienes in the airways.]

Sodium cromoglycate

[Crom-Ophtal eye drops® [ Sanbe Vision ]  


beclomethasone
[Beclometasone controls the rate of protein synthesis, depresses the migration of polymorphonuclear leukocytes, fibroblasts, reverses capillary permeability and lysosomal stabilisation at the cellular level to prevent or control inflammation.]
Cleniderm cream® [ Soho ]

formoterol
[Formoterol relaxes the bronchial smooth muscle by selectively acting on β2-receptors with minimal effect on heart rate. It has a long-acting effect.]

salmeterol
[Salmeterol is a direct-acting sympathomimetic which relaxes bronchial smooth muscle by its selective action on β2 receptors with little effect on heart rate.]

ipratropium bromide  
[Ipratropium bromide blocks the action of acetylcholine at parasympathetic sites in bronchial smooth muscle causing bronchodilation.]
Atrovent inhaler® [ Boehringer Ingelheim ]

methylprednisolon
Advantan cream, comedrol, dll.